THE HEALTHPLACE
A Private Medical Practice of David P. Kalin, M.D., M.P.H.
P.O. Box 6009
Palm Harbor, Fl 34684
Tel  813.966.1431
  Fax 813.925.1932

drkalin@drkalin.com

 

What Causes Cancer, Anyhow?

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hat causes cancer, anyhow? Many of us have experienced the dread, the disdain, the sadness, and the urgency associated with cancer.  What do I do now, Doc ... surgery tomorrow... malignant melanoma, transitional nevus ... they said a wider resection.  What does it all mean?  What?, lumps in the neck, poor guy, died in six months.  Stomach cancer, skin, colon, prostate, liver, ovary, brain, pancreas, bone, blood ...where else can it go?  What is it and why? Could you check me, Doc? No, I didn’t notice that mass in my belly ... the size of a basketball? Huh.... not the “Big C” I hope. Is it, Doc?

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ou say the doctor just examined you and now you have a discharge and a lump in your breast and your dad died of prostate cancer and you have trouble swallowing and fluids are filling up in your lungs...”metastases all over?” Who said it was benign?

And you don’t want to go to the hospital and today you’re weak and yesterday you were strong and you lost 20 lbs. last month without a change in diet. Yes, blood is scary. Maybe it isn’t just hemorrhoids ... the family has a history of colon cancer and the polyps are what?...”pre-malignant?” What about the venereal warts and these “things on the skin?” And have you heard of sarcoma, carcinoma and leukemia!

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hat is cancer and why do we worry about it? What causes it, how do we recognize it and what do we do about it’? What does cancer tell us about our lives and our relationships to life?

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s a consortium of cells in a balance of growth and destruction through an innate system of control, we are constantly repairing ourselves from the onslaught of environmental forces, As the process of pain and inflammation leads to the healing process, a controlling influence brings order out of disorder, an eventual resting state whereby rapidly multiplying cells remodel into newly synthesized fibers and tissues producing purposeful structural patterns such as blood vessels, ligaments, and bone. Cancer represents a failure of this process to achieve such a resting state. Benign means non-cancerous (non-spreading), where as malignant means cancerous with the potential for spreading uncontrollably to neighboring tissues. Cancer of the bone or muscle is a sarcoma. A carcinoma is a cancer of the skin glands and linings of the lung, liver, bladder, and brain. Leukemia is a cancer of the blood.

Cancer is the second most common cause of death (first is heart disease). One in every 5, 3.5 million in the 1970’s died of cancer. Although some would argue about the definition of a cancer cure, early surgical removal of various cancers often leads to a cure. Experts say cancers of the cervix have an almost 100% cure, Hodgkin’s Disease (disease of the white blood cells) an 80% cure, and colon cancer, malignant melanoma, and acute lymphocytic leukemia a 50% cure.

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any environmental factors are considered carcinogenic (cancer causing), especially industrial materials such as asbestos, occupational nickel, chrome, vinyl chloride, rubber, and some chlorinated chemicals. Other environmental factors considered carcinogenic include radioactivity, smoke, ultraviolet light, alcohol, tobacco, estrogens, fat, viruses, and nitrosamines.  A family history may predispose one to cancer via the oncogenes, the body’s genetic control system. Cancers of the breast, colon and prostate appear to have a familial or genetic component.

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he development of cancer is thought to be the end product of an interplay or modulation of these two forces - environment and genetics.  Cells are transformed to cancer as bacteria, toxins, and other environmental stresses lead to chronic inflammation (or aggravation) of our susceptible organ systems. Pre-malignant polyps change to colon cancer; inflammatory cells of the cervix turn to cervical carcinoma and the skin’s solar damage advances to basal cell cancer.

 

We should all be aware of the cancer’s most common warning signals:

A CHANGE IN BOWEL OR BLADDER HABITS

A NON-HEALING SORE

UNUSUAL BLEEDING OR DISCHARGE

A THICKENING OR LUMP IN BREAST OR ELSEWHERE

INDIGESTION OR DIFFICULTY IN SWALLOWING

AN OBVIOUS CHANGEIN A WART OR MOLE

A NAGGING COUGH OR HOARSENESS

SIGNIFICANT WEIGHT LOSS

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amiliar tests for cancer include a colorectal test for occult blood in the stool, a pap smear of the cervix, and a mammogram for breast cancer detection.  The American Cancer Society recommends three stool tests for the early detection of colon and rectal cancer in people without symptoms.  A stool test is recommended every year after 40 and a proctoscopy (fiberoptic scope up the rectum) should be carried out every three to five years after the age of 50.  A cervical pap smear should be performed for sexually active women who have reached 18 and annually thereafter until three or more consecutive normal pap smears have been performed and thereafter at the discretion of the physician.  A monthly self-breast examination is recommended for all women and a mammogram for asymptomatic women every year after with a baseline mammogram between 35 and 39; the mammogram should be done every I to 2 years depending on the findings for women 40 to 49.

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ore sophisticated diagnostic modalities include magnetic resonance imaging, endoscopic ultrasound, CAT scanning, positive emission tomography, monoclonal antibodies, tissue cultures, radioisotope immunoassays, and fine needle aspiration.

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nce cancer is recognized, many treatments are available. Some are traditional and others are more, “modern” or even experimental. Such treatments include early tumor mapping to enhance surgical excision and laser treatment for eradication of abnormal cells or the boring of a hole through an inoperable tumor in the esophagus or rectum. Chemo and hormone therapy are used to minimize the spread of secondary tumors and to “mop up” after surgical removal of a tumor. Other technologies include bone marrow transplantation for aplastic anemia and leukemia and hyperthermia - using heat to increase the temperature of the body to kill cancer cells.

Ongoing research includes genetic fusing of cancer cells with normal cells to produce specific cancer-seeking antibodies and immunotherapy and nutrition to enhance the body’s own disease fighting capability.

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hen all is said and done we may ask “why me?”… “is it so?”  Are the symptoms of cancer our deepest dreams coming true? Does stoisism and the turning in on one’s self lead to cancer’s unchecked growth’? Is cancer a manifestation of a cellular lack of power within the total organism? Do anxiety and then denial lead to a biotransforrmation and an inability to survive the effects of surrounding cells? Maybe, yes...and if we are able to rely on our innate sense of faith and life to balance our energies, we can perhaps enhance our immune system and build the physiologic component of trust which links together the welfare of the individual cell and the total organism.

In the meantime ... let’s burn off that mole ...

 

                                              Eh, what’s up, doc?...

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